Phosphoinositides regulate ion channels
نویسندگان
چکیده
منابع مشابه
Phosphoinositides regulate P2X4 ATP-gated channels through direct interactions.
P2X receptors are ATP-gated nonselective cation channels highly permeable to calcium that contribute to nociception and inflammatory responses. The P2X(4) subtype, upregulated in activated microglia, is thought to play a critical role in the development of tactile allodynia following peripheral nerve injury. Posttranslational regulation of P2X(4) function is crucial to the cellular mechanisms o...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
سال: 2015
ISSN: 1388-1981
DOI: 10.1016/j.bbalip.2014.09.010